hMAO-B-IN-4
Modify Date: 2024-04-03 10:45:40
hMAO-B-IN-4 structure
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Common Name | hMAO-B-IN-4 | ||
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| CAS Number | 1666119-75-0 | Molecular Weight | 320.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H16O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of hMAO-B-IN-4hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research[1]. |
| Name | hMAO-B-IN-4 |
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| Description | hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research[1]. |
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| Related Catalog | |
| In Vitro | hMAO-B-IN-4 (0-40 μM) 对 hMAO-B 相比于 hMAO-A 具有高选择性，SI 值为 504.791[1]。 hMAO-B-IN-4 (0-40 μM) 抑制 hMAO-A 和 hMAO-B，IC50 值分别为 33.821 和 0.067 μM[1]。 |
| References |
| Molecular Formula | C20H16O2S |
|---|---|
| Molecular Weight | 320.40 |
| InChIKey | MKSMRBDQELHEBO-JLHYYAGUSA-N |
| SMILES | O=C(C=Cc1ccc(OCc2ccccc2)cc1)c1cccs1 |