N3-PEG3-CH2CH2-Boc
Modify Date: 2025-09-03 15:34:36
N3-PEG3-CH2CH2-Boc structure
|
Common Name | N3-PEG3-CH2CH2-Boc | ||
|---|---|---|---|---|
| CAS Number | 252881-73-5 | Molecular Weight | 303.35500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H25N3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of N3-PEG3-CH2CH2-BocN3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. |
| Name | N3(CH2CH2O)3CH2CH2COOt-Bu |
|---|---|
| Synonym | More Synonyms |
| Description | N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C13H25N3O5 |
|---|---|
| Molecular Weight | 303.35500 |
| Exact Mass | 303.17900 |
| PSA | 103.74000 |
| LogP | 1.53106 |
| Hazard Codes | Xi |
|---|
| Precursor 0 | |
|---|---|
| DownStream 1 | |
CAS#:252881-74-6| tert-butyl 12-azido-4,7,10-trioxadodecanoate |
| tert-butyl 12-azido-4,7,10-trioxadocecanoate |
| 12-azido-4,7,10-trioxadodecanoic acid tert-butyl ester |
| 3-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-propionic acid tert-butyl ester |
| N3-PEG3-CH2CH2COOtBu |
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- Shanghai Nianxing Industrial Co., Ltd
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- DC Chemicals Limited
- China
- Product Name: N3-PEG3-CH2CH2-Boc
- Price: $Inquiry/1g
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- Email: sales@dcchemicals.com
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