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1260092-46-3

1260092-46-3 structure
1260092-46-3 structure
  • Name: NH2-PEG1-CH2CH2-Boc
  • Chemical Name: 2-Methyl-2-propanyl 3-(2-aminoethoxy)propanoate
  • CAS Number: 1260092-46-3
  • Molecular Formula: C9H19NO3
  • Molecular Weight: 189.252
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-26 00:57:02
  • Modify Date: 2024-01-10 15:53:28
  • NH2-PEG1-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name 2-Methyl-2-propanyl 3-(2-aminoethoxy)propanoate
Synonyms MFCD20727480
Propanoic acid, 3-(2-aminoethoxy)-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 3-(2-aminoethoxy)propanoate
Description NH2-PEG1-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Qiu X, et al. Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Org Lett. 2019 May 17;21(10):3838-3841.

Density 1.0±0.1 g/cm3
Boiling Point 264.9±15.0 °C at 760 mmHg
Molecular Formula C9H19NO3
Molecular Weight 189.252
Flash Point 90.5±16.7 °C
Exact Mass 189.136490
LogP 0.84
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.445
Hazard Codes Xn