FGFR-IN-3

Modify Date: 2025-08-26 21:59:46

FGFR-IN-3 structure	Common Name	FGFR-IN-3
	CAS Number	2488762-63-4	Molecular Weight	383.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₇F₂N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FGFR-IN-3

FGFR-IN-3 (compound 6) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-3 shows neuroprotective activity. FGFR-IN-3 can be used for neurodegenerative diseases research[1].

Name	FGFR-IN-3

Description	FGFR-IN-3 (compound 6) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-3 shows neuroprotective activity. FGFR-IN-3 can be used for neurodegenerative diseases research[1].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR Research Areas >> Neurological Disease
In Vivo	FGFR-IN-3 (compound 6) is sufficiently lipophilic (logP = 2.2) to passively permeate across the blood-brain barrier, and further increase in molecular lipophilicity results in boosting MBI (mechanism-based inactivation) activity[1].
References	[1]. Sakai H, et al. Fibroblast growth factor receptor modulators employing diamines with reduced phospholipidosis-inducing potential. Bioorg Med Chem. 2020 Jul 15;28(14):115562.

Molecular Formula	C₁₈H₂₇F₂N₅O₂
Molecular Weight	383.44

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FGFR-IN-3

Use of FGFR-IN-3

Names

FGFR-IN-3 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.