FGFR-IN-7

Modify Date: 2024-01-10 18:28:03

FGFR-IN-7 structure	Common Name	FGFR-IN-7
	CAS Number	2488764-17-4	Molecular Weight	374.81
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₂₁ClF₂N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FGFR-IN-7

FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-7 shows neuroprotective activity. FGFR-IN-7 improves brain exposure and reduced risk of phospholidosis. FGFR-IN-7 can be used for neurodegenerative diseases research[1].

Name	FGFR-IN-7

Description	FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-7 shows neuroprotective activity. FGFR-IN-7 improves brain exposure and reduced risk of phospholidosis. FGFR-IN-7 can be used for neurodegenerative diseases research[1].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR Research Areas >> Neurological Disease
In Vivo	FGFR-IN-7 (compound 17) (1 mg/kg, Orally, once daily for 10 days) significantly enhances recovery of coordinated movement in the in vivo rat acute stroke model[1].
References	[1]. Sakai H, et al. Fibroblast growth factor receptor modulators employing diamines with reduced phospholipidosis-inducing potential. Bioorg Med Chem. 2020 Jul 15;28(14):115562.

Molecular Formula	C₁₆H₂₁ClF₂N₄O₂
Molecular Weight	374.81

FGFR-IN-7

Use of FGFR-IN-7

Names

FGFR-IN-7 Biological Activity

Chemical & Physical Properties