spongosine

Modify Date: 2025-08-25 12:41:00

spongosine Structure
spongosine structure
 Common Name spongosine
CAS Number 24723-77-1 Molecular Weight 297.27
Density 1.98g/cm3 Boiling Point 705ºC at 760mmHg
Molecular Formula C11H15N5O5 Melting Point N/A
MSDS N/A Flash Point 380.2ºC

 Use of spongosine


Spongosine (2-Methoxyadenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-Methoxyadenosine
Synonym More Synonyms

 spongosine Biological Activity

Description Spongosine (2-Methoxyadenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.98g/cm3
Boiling Point 705ºC at 760mmHg
Molecular Formula C11H15N5O5
Molecular Weight 297.27
Flash Point 380.2ºC
Exact Mass 297.10700
PSA 148.77000
Vapour Pressure 7.3E-21mmHg at 25°C
Index of Refraction 1.829

 Synthetic Route

 Synonyms

9H-purin-6-amine
2-Methoxy-adenosin
2-methoxy-adenosine
Spongosine
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