PIM1-IN-6

Modify Date: 2025-09-02 23:46:44

PIM1-IN-6 structure	Common Name	PIM1-IN-6
	CAS Number	2439168-69-9	Molecular Weight	418.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₈N₆O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PIM1-IN-6

PIM1-IN-6 (compound 5h) is a potent PIM-1 inhibitor, with an IC50 of 0.60 μM. PIM1-IN-6 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 1.51 and 15.2 μM, respectively[1].

Name	PIM1-IN-6

Description	PIM1-IN-6 (compound 5h) is a potent PIM-1 inhibitor, with an IC50 of 0.60 μM. PIM1-IN-6 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 1.51 and 15.2 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> Pim
Target	PIM1:0.60 μM (IC50)
References	[1]. Philoppes JN, et al. New pyrazolopyrimidine derivatives with anticancer activity: Design, synthesis, PIM-1 inhibition, molecular docking study and molecular dynamics. Bioorg Chem. 2020 Jul;100:103944.

Molecular Formula	C₂₁H₁₈N₆O₄
Molecular Weight	418.41

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