PIM1-IN-6

Modify Date: 2025-09-02 23:46:44

PIM1-IN-6 Structure
PIM1-IN-6 structure
 Common Name PIM1-IN-6
CAS Number 2439168-69-9 Molecular Weight 418.41
Density N/A Boiling Point N/A
Molecular Formula C21H18N6O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PIM1-IN-6


PIM1-IN-6 (compound 5h) is a potent PIM-1 inhibitor, with an IC50 of 0.60 μM. PIM1-IN-6 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 1.51 and 15.2 μM, respectively[1].

 Names

Name PIM1-IN-6

 PIM1-IN-6 Biological Activity

Description PIM1-IN-6 (compound 5h) is a potent PIM-1 inhibitor, with an IC50 of 0.60 μM. PIM1-IN-6 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 1.51 and 15.2 μM, respectively[1].
Related Catalog
Target

PIM1:0.60 μM (IC50)

References

[1]. Philoppes JN, et al. New pyrazolopyrimidine derivatives with anticancer activity: Design, synthesis, PIM-1 inhibition, molecular docking study and molecular dynamics. Bioorg Chem. 2020 Jul;100:103944.

 Chemical & Physical Properties

Molecular Formula C21H18N6O4
Molecular Weight 418.41
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Chemsrc provides PIM1-IN-6(CAS#:2439168-69-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of PIM1-IN-6 are included as well.>> amp version: PIM1-IN-6

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