2439168-72-4

2439168-72-4 structure

2439168-72-4 structure

Name: PIM1-IN-7
Chemical Name: PIM1-IN-7
CAS Number: 2439168-72-4
Molecular Formula: C₂₃H₂₃N₅O
Molecular Weight: 385.46
Catalog: Signaling Pathways JAK/STAT Signaling Pim
Create Date: 2022-08-15 21:06:42
Modify Date: 2024-01-09 20:33:23
PIM1-IN-7 (compound 6c) is a potent PIM-1 inhibitor, with an IC50 of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 42.9 and 7.68 μM, respectively[1].

Name	PIM1-IN-7

Description	PIM1-IN-7 (compound 6c) is a potent PIM-1 inhibitor, with an IC50 of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 42.9 and 7.68 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> Pim
Target	PIM1:0.67 μM (IC50)
References	[1]. Philoppes JN, et al. New pyrazolopyrimidine derivatives with anticancer activity: Design, synthesis, PIM-1 inhibition, molecular docking study and molecular dynamics. Bioorg Chem. 2020 Jul;100:103944.

Molecular Formula	C₂₃H₂₃N₅O
Molecular Weight	385.46