2439168-69-9

2439168-69-9 structure

2439168-69-9 structure

Name: PIM1-IN-6
Chemical Name: PIM1-IN-6
CAS Number: 2439168-69-9
Molecular Formula: C₂₁H₁₈N₆O₄
Molecular Weight: 418.41
Catalog: Signaling Pathways JAK/STAT Signaling Pim
Create Date: 2022-08-18 06:47:56
Modify Date: 2023-02-23 11:52:32
PIM1-IN-6 (compound 5h) is a potent PIM-1 inhibitor, with an IC50 of 0.60 μM. PIM1-IN-6 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 1.51 and 15.2 μM, respectively[1].

Name	PIM1-IN-6

Description	PIM1-IN-6 (compound 5h) is a potent PIM-1 inhibitor, with an IC50 of 0.60 μM. PIM1-IN-6 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 1.51 and 15.2 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> Pim
Target	PIM1:0.60 μM (IC50)
References	[1]. Philoppes JN, et al. New pyrazolopyrimidine derivatives with anticancer activity: Design, synthesis, PIM-1 inhibition, molecular docking study and molecular dynamics. Bioorg Chem. 2020 Jul;100:103944.

Molecular Formula	C₂₁H₁₈N₆O₄
Molecular Weight	418.41