JH-XIV-68-3

Modify Date: 2024-01-10 10:12:42

JH-XIV-68-3 Structure
JH-XIV-68-3 structure
 Common Name JH-XIV-68-3
CAS Number 2426628-52-4 Molecular Weight 454.41
Density N/A Boiling Point N/A
Molecular Formula C21H17F3N8O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JH-XIV-68-3


JH-XIV-68-3 is a selective macrocyclic inhibitor of DYRK1A/B. JH-XIV-68-3 displays selectivity for DYRK1A and close family member DYRK1B in biochemical and cellular assays. JH-XIV-68-3 demonstrates antitumor efficacy in head and neck squamous cell carcinoma (HNSCC) cell lines[1].

 Names

Name JH-XIV-68-3

 JH-XIV-68-3 Biological Activity

Description JH-XIV-68-3 is a selective macrocyclic inhibitor of DYRK1A/B. JH-XIV-68-3 displays selectivity for DYRK1A and close family member DYRK1B in biochemical and cellular assays. JH-XIV-68-3 demonstrates antitumor efficacy in head and neck squamous cell carcinoma (HNSCC) cell lines[1].
Related Catalog
References

[1]. Powell CE, et al. Selective Macrocyclic Inhibitors of DYRK1A/B. ACS Med Chem Lett. 2022;13(4):577-585.

 Chemical & Physical Properties

Molecular Formula C21H17F3N8O
Molecular Weight 454.41
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Chemsrc provides JH-XIV-68-3(CAS#:2426628-52-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of JH-XIV-68-3 are included as well.>> amp version: JH-XIV-68-3

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