BChE-IN-17

Modify Date: 2024-11-29 17:45:07

BChE-IN-17 structure	Common Name	BChE-IN-17
	CAS Number	2425632-57-9	Molecular Weight	535.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₃BrN₂O₄S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BChE-IN-17

BChE-IN-17 (compound 6n) is a potent and selective BChE inhibitor with IC50s of 10.5 nM and 32.5 nM for eqBChE and hBChE, respectively. BChE-IN-17 shows over 1000-fold selectivity to BChE against AChE. BChE-IN-17 shows low neurotoxicity and moderate neuroprotective effects[1].

Name	BChE-IN-17

Description	BChE-IN-17 (compound 6n) is a potent and selective BChE inhibitor with IC50s of 10.5 nM and 32.5 nM for eqBChE and hBChE, respectively. BChE-IN-17 shows over 1000-fold selectivity to BChE against AChE. BChE-IN-17 shows low neurotoxicity and moderate neuroprotective effects[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	eqBCHE:10.5 nM (IC50) hBCHE:32.5 nM (IC50) eel AChE:686.4 μM (IC50)
References	[1]. Tingkai Chen, et al. The structural modification and biological evaluation of tetrahydrothienopyridine derivatives as selective BChE inhibitors. Bioorg Med Chem Lett. 2023 Sep 1;93:129436.

Molecular Formula	C₂₃H₂₃BrN₂O₄S₂
Molecular Weight	535.47

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BChE-IN-17

Use of BChE-IN-17

Names

BChE-IN-17 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.