Mt KARI-IN-4

Modify Date: 2025-08-27 13:09:39

Mt KARI-IN-4 structure	Common Name	Mt KARI-IN-4
	CAS Number	2413974-53-3	Molecular Weight	365.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₈FN₅O₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Mt KARI-IN-4

Mt KARI-IN-4 (compound 5c) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with a Ki value of 5.48 μM. Mt KARI-IN-4 has inhibitory activity against Mtb H37Rv (MIC = 0.78 μM) and low cytotoxicity (HEK IC50 > 72 μg/mL)[1].

Name	Mt KARI-IN-4

Description	Mt KARI-IN-4 (compound 5c) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with a Ki value of 5.48 μM. Mt KARI-IN-4 has inhibitory activity against Mtb H37Rv (MIC = 0.78 μM) and low cytotoxicity (HEK IC50 > 72 μg/mL)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	Ki: 5.48 μM (Mtb KARI)[1]
References	[1]. Krishna VS, et al. Design and development of ((4-methoxyphenyl)carbamoyl) (5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl)amide analogues as Mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors. Eur J Med Chem. 2020;193:112178.

Molecular Formula	C₁₃H₈FN₅O₃S₂
Molecular Weight	365.36

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Mt KARI-IN-4

Use of Mt KARI-IN-4

Names

Mt KARI-IN-4 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.