219138-24-6

219138-24-6 structure
219138-24-6 structure
  • Name: p38 MAPK-IN-4
  • Chemical Name: 2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1,2-dihydro -3H-pyrazol-3-one
  • CAS Number: 219138-24-6
  • Molecular Formula: C20H13ClFN3O
  • Molecular Weight: 365.78800
  • Catalog: Signaling Pathways MAPK/ERK Pathway p38 MAPK
  • Create Date: 2016-02-26 09:55:50
  • Modify Date: 2024-01-12 11:39:34
  • p38 MAPK-IN-4 (compound 6) is a p38 MAPK inhibitor with an 50 of 35 nM[1].

Name 2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1,2-dihydro -3H-pyrazol-3-one
Description p38 MAPK-IN-4 (compound 6) is a p38 MAPK inhibitor with an 50 of 35 nM[1].
Related Catalog
Target

p38:35 nM (IC50)

References

[1]. S E de Laszlo, et al. Pyrroles and other heterocycles as inhibitors of p38 kinase. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2689-94.  

Molecular Formula C20H13ClFN3O
Molecular Weight 365.78800
Exact Mass 365.07300
PSA 50.68000
LogP 4.68710