(S)-PI3Kα-IN-4
Modify Date: 2025-10-18 13:15:22
(S)-PI3Kα-IN-4 structure
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Common Name | (S)-PI3Kα-IN-4 | ||
|---|---|---|---|---|
| CAS Number | 2322293-84-3 | Molecular Weight | 560.00 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H23ClFN5O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (S)-PI3Kα-IN-4(S)-PI3Kα-IN-4 is a potent inhibitor of PI3Kα, with an IC50 of 2.3 nM. (S)-PI3Kα-IN-4 shows 38.3-, 4.25-, and 4.93-fold selectivity for PI3Kα over PI3Kβ, PI3Kδ, and PI3Kγ, respectively. (S)-PI3Kα-IN-4 can be used for the research of cancer. |
| Name | (S)-PI3Kα-IN-4 |
|---|
| Description | (S)-PI3Kα-IN-4 is a potent inhibitor of PI3Kα, with an IC50 of 2.3 nM. (S)-PI3Kα-IN-4 shows 38.3-, 4.25-, and 4.93-fold selectivity for PI3Kα over PI3Kβ, PI3Kδ, and PI3Kγ, respectively. (S)-PI3Kα-IN-4 can be used for the research of cancer. |
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| Molecular Formula | C25H23ClFN5O5S |
|---|---|
| Molecular Weight | 560.00 |
| InChIKey | LPATWVFSBNDSHR-AWEZNQCLSA-N |
| SMILES | CNC(=O)C(C)Cn1cnc2ccc(-c3cnc(OC)c(NS(=O)(=O)c4ccc(F)cc4Cl)c3)cc2c1=O |