Py-MPB-amino-C3-PBD
Modify Date: 2024-01-02 22:17:38
Py-MPB-amino-C3-PBD structure
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Common Name | Py-MPB-amino-C3-PBD | ||
|---|---|---|---|---|
| CAS Number | 2412924-07-1 | Molecular Weight | 744.84 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C41H44N8O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Py-MPB-amino-C3-PBDPy-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Py-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity[1]. |
| Name | Py-MPB-amino-C3-PBD |
|---|
| Description | Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Py-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity[1]. |
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| Related Catalog | |
| Target |
Pyrrolobenzodiazepines |
| In Vitro | Py-MPB-amino-C3-PBD (compound 73) shows cytotoxicity with IC50s of 301, 144.1 and 37.5 nM for U138-MG, A431, and REH cells, respectively. Py-MPB-amino-C3-PBD possesses potent anti-bacterial effects against the gram negative strain E. coli K12, with potency of 2 pg/mL determined[1]. |
| References |
[1]. David Edwin Thurston, et al. Polycyclic amides as cytotoxic agents. WO2020049286A1. |
| Molecular Formula | C41H44N8O6 |
|---|---|
| Molecular Weight | 744.84 |