THK-5470 structure
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Common Name | THK-5470 | ||
|---|---|---|---|---|
| CAS Number | 2410554-04-8 | Molecular Weight | 312.34 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H17FN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of THK-5470THK-5470, a monoamine oxidase-B (MAO-B) imaging probe, could be used for neurological diseases study. THK-5470 shows remarkably high binding affinity against MAO-B with an IC50 value of 4.2 nM, low binding affinity against tau with an IC50 value of 4462 nM. THK-5470 has high selective binding property and high affinity (from patent EP2019-846498). |
| Name | THK-5470 |
|---|
| Description | THK-5470, a monoamine oxidase-B (MAO-B) imaging probe, could be used for neurological diseases study. THK-5470 shows remarkably high binding affinity against MAO-B with an IC50 value of 4.2 nM, low binding affinity against tau with an IC50 value of 4462 nM. THK-5470 has high selective binding property and high affinity (from patent EP2019-846498). |
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| Related Catalog | |
| Target |
THK-5470 shows remarkably high binding affinity against MAO-B with an IC50 value of 4.2 nM, low binding affinity against tau with an IC50 value of 4462 nM. |
| Molecular Formula | C18H17FN2O2 |
|---|---|
| Molecular Weight | 312.34 |