2410554-04-8
2410554-04-8 structure
- Name: THK-5470
- Chemical Name: THK-5470
- CAS Number: 2410554-04-8
- Molecular Formula: C18H17FN2O2
- Molecular Weight: 312.34
- Catalog: Research Areas Neurological Disease
- Create Date: 2021-10-30 00:20:30
- Modify Date: 2025-09-03 11:12:22
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THK-5470, a monoamine oxidase-B (MAO-B) imaging probe, could be used for neurological diseases study. THK-5470 shows remarkably high binding affinity against MAO-B with an IC50 value of 4.2 nM, low binding affinity against tau with an IC50 value of 4462 nM. THK-5470 has high selective binding property and high affinity (from patent EP2019-846498).
| Name | THK-5470 |
|---|
| Description | THK-5470, a monoamine oxidase-B (MAO-B) imaging probe, could be used for neurological diseases study. THK-5470 shows remarkably high binding affinity against MAO-B with an IC50 value of 4.2 nM, low binding affinity against tau with an IC50 value of 4462 nM. THK-5470 has high selective binding property and high affinity (from patent EP2019-846498). |
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| Related Catalog | |
| Target |
THK-5470 shows remarkably high binding affinity against MAO-B with an IC50 value of 4.2 nM, low binding affinity against tau with an IC50 value of 4462 nM. |
| Molecular Formula | C18H17FN2O2 |
|---|---|
| Molecular Weight | 312.34 |