Mu opioid receptor antagonist 7

Modify Date: 2024-09-16 11:51:47

Mu opioid receptor antagonist 7 Structure
Mu opioid receptor antagonist 7 structure
Common Name Mu opioid receptor antagonist 7
CAS Number 2378397-30-7 Molecular Weight 386.91
Density N/A Boiling Point N/A
Molecular Formula C22H27ClN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mu opioid receptor antagonist 7


Mu opioid receptor antagonist 7 (compound 24) is a potent and CNS permeable antagonist of µOR (µ-opioid receptor), with an IC50 of 29 ± 3.0 nM. Mu opioid receptor antagonist 7 can be used for the research of pain and opioid use disorder[1].

 Names

Name Mu opioid receptor antagonist 7

 Mu opioid receptor antagonist 7 Biological Activity

Description Mu opioid receptor antagonist 7 (compound 24) is a potent and CNS permeable antagonist of µOR (µ-opioid receptor), with an IC50 of 29 ± 3.0 nM. Mu opioid receptor antagonist 7 can be used for the research of pain and opioid use disorder[1].
Related Catalog
Target

μ Opioid Receptor/MOR:29 ± 3.0 nM (IC50)

References

[1]. Nerurkar A, et al. Novel series of tunable µOR modulators with enhanced brain penetration for the treatment of opioid use disorder, pain and neuropsychiatric indications. Bioorg Med Chem Lett. 2023 Aug 15;92:129405.  

 Chemical & Physical Properties

Molecular Formula C22H27ClN2O2
Molecular Weight 386.91
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.