2378397-30-7

2378397-30-7 structure

Name: Mu opioid receptor antagonist 7
Chemical Name: Mu opioid receptor antagonist 7
CAS Number: 2378397-30-7
Molecular Formula: C₂₂H₂₇ClN₂O₂
Molecular Weight: 386.91
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2024-09-16 11:51:47
Modify Date: 2024-09-16 11:51:47
Mu opioid receptor antagonist 7 (compound 24) is a potent and CNS permeable antagonist of µOR (µ-opioid receptor), with an IC50 of 29 ± 3.0 nM. Mu opioid receptor antagonist 7 can be used for the research of pain and opioid use disorder[1].

Name	Mu opioid receptor antagonist 7

Description	Mu opioid receptor antagonist 7 (compound 24) is a potent and CNS permeable antagonist of µOR (µ-opioid receptor), with an IC50 of 29 ± 3.0 nM. Mu opioid receptor antagonist 7 can be used for the research of pain and opioid use disorder[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
Target	μ Opioid Receptor/MOR:29 ± 3.0 nM (IC50)
References	[1]. Nerurkar A, et al. Novel series of tunable µOR modulators with enhanced brain penetration for the treatment of opioid use disorder, pain and neuropsychiatric indications. Bioorg Med Chem Lett. 2023 Aug 15;92:129405.

Molecular Formula	C₂₂H₂₇ClN₂O₂
Molecular Weight	386.91