DCN1-UBC12-IN-3

Modify Date: 2024-01-10 18:24:57

DCN1-UBC12-IN-3 Structure
DCN1-UBC12-IN-3 structure
Common Name DCN1-UBC12-IN-3
CAS Number 2374827-45-7 Molecular Weight 614.74
Density N/A Boiling Point N/A
Molecular Formula C30H30N8O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DCN1-UBC12-IN-3


DCN1-UBC12-IN-3 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.25 nM. Anticardiac fibrotic effect[1].

 Names

Name DCN1-UBC12-IN-3

 DCN1-UBC12-IN-3 Biological Activity

Description DCN1-UBC12-IN-3 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.25 nM. Anticardiac fibrotic effect[1].
Related Catalog
In Vitro DCN1-UBC12-IN-3 (compound 49) possesses low cytotoxicity toward cardiac fibroblasts (CFs) with an IC50 of 2578 μM for 24 h[1].
References

[1]. He ZX, et al. Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects. J Med Chem. 2022;65(1):163-190.

 Chemical & Physical Properties

Molecular Formula C30H30N8O3S2
Molecular Weight 614.74