DC Chemicals Limited
China
Product Name: DCN1-UBC12-IN-1
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2374827-31-1

2374827-31-1 structure

2374827-31-1 structure

Name: DCN1-UBC12-IN-1
Chemical Name: DCN1-UBC12-IN-1
CAS Number: 2374827-31-1
Molecular Formula: C₂₄H₂₃N₇O₃S₂
Molecular Weight: 521.61
Catalog: Signaling Pathways Metabolic Enzyme/Protease E1/E2/E3 Enzyme
Create Date: 2022-04-07 19:36:54
Modify Date: 2024-01-06 18:46:52
DCN1-UBC12-IN-1 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.86 nM. Anticardiac fibrotic effect[1].

Name	DCN1-UBC12-IN-1

Description	DCN1-UBC12-IN-1 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.86 nM. Anticardiac fibrotic effect[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> E1/E2/E3 Enzyme
In Vitro	DCN1-UBC12-IN-1 (compound 44) possesses low cytotoxicity toward cardiac fibroblasts (CFs) with an IC50 of 9.97 μM for 24 h[1].
References	[1]. He ZX, et al. Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects. J Med Chem. 2022;65(1):163-190.

Molecular Formula	C₂₄H₂₃N₇O₃S₂
Molecular Weight	521.61