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2374827-45-7

2374827-45-7 structure
2374827-45-7 structure
  • Name: DCN1-UBC12-IN-3
  • Chemical Name: DCN1-UBC12-IN-3
  • CAS Number: 2374827-45-7
  • Molecular Formula: C30H30N8O3S2
  • Molecular Weight: 614.74
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease E1/E2/E3 Enzyme
  • Create Date: 2022-04-27 17:05:53
  • Modify Date: 2025-08-26 09:17:14
  • DCN1-UBC12-IN-3 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.25 nM. Anticardiac fibrotic effect[1].
Name DCN1-UBC12-IN-3
Description DCN1-UBC12-IN-3 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.25 nM. Anticardiac fibrotic effect[1].
Related Catalog
In Vitro DCN1-UBC12-IN-3 (compound 49) possesses low cytotoxicity toward cardiac fibroblasts (CFs) with an IC50 of 2578 μM for 24 h[1].
References

[1]. He ZX, et al. Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects. J Med Chem. 2022;65(1):163-190.

Molecular Formula C30H30N8O3S2
Molecular Weight 614.74
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title: CAS No. 2374827-45-7 | Chemsrc address: https://www.chemsrc.com/en/baike/1704812.html

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