5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine structure
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Common Name | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine | ||
|---|---|---|---|---|
| CAS Number | 23669-79-6 | Molecular Weight | 530.56800 | |
| Density | 1.294 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C30H30N2O7 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks[1][2]. |
| Name | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine |
|---|---|
| Synonym | More Synonyms |
| Description | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks[1][2]. |
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| Related Catalog | |
| Target |
Ki: >1000 μM (E. coli dUTPase)[1] |
| References |
| Density | 1.294 g/cm3 |
|---|---|
| Molecular Formula | C30H30N2O7 |
| Molecular Weight | 530.56800 |
| Exact Mass | 530.20500 |
| PSA | 112.01000 |
| LogP | 3.21090 |
| Appearance of Characters | Powder | White to Off-white |
| Index of Refraction | 1.61 |
| Storage condition | −20°C |
| Water Solubility | Soluble in acetonitrile at 20mg/ml |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H332-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R20/22;R36/37/38 |
| Safety Phrases | S22-S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
~10%
5'-O-(4,4'-Dime... CAS#:23669-79-6 |
| Literature: Avino, Anna; Garcia, Ramon Gueimil; Albericio, Fernando; Mann, Matthias; Wilm, Matthias; Neubauer, Gitte; Eritja, Ramon Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 10 p. 1649 - 1658 |
|
~%
5'-O-(4,4'-Dime... CAS#:23669-79-6 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 4 p. 1181 - 1184 |
|
~%
5'-O-(4,4'-Dime... CAS#:23669-79-6 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 4 p. 1181 - 1184 |
|
~%
5'-O-(4,4'-Dime... CAS#:23669-79-6 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 4 p. 1181 - 1184 |
CAS#:76512-82-8| 5'-O-[Bis(4-methoxyphenyl)benzyl]-2'-deoxyuridine |
| 5'-O-Dimethylterephthale-2'-deoxyuridine |
| 5'-(4,4'-dimethoxytrityl)-2'-deoxyuridine |
| 5'-O-DMT-2'-DEOXYURIDINE |
| 2'-deoxy-5'-O-dimethoxytrityluridine |
| DMT-DEOXYURIDINE |
| 2'-deoxy-5'-(4,4'-dimethoxytrityl)uridine |
| 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxyuridine |
| dmt-du |
| 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-uridine |
| 5'-O-(4,4'-dimetoxytrityl)-2'-deoxyuridine |
| 2'-Deoxy-5'-O-DMT-uridine |