(S,R,S)-AHPC-C8-NH2

Modify Date: 2024-04-05 11:03:46

(S,R,S)-AHPC-C8-NH2 Structure
(S,R,S)-AHPC-C8-NH2 structure
Common Name (S,R,S)-AHPC-C8-NH2
CAS Number 2341796-79-8 Molecular Weight 585.80
Density N/A Boiling Point N/A
Molecular Formula C31H47N5O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S,R,S)-AHPC-C8-NH2


(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1[1].

 Names

Name (S,R,S)-AHPC-C8-NH2

 (S,R,S)-AHPC-C8-NH2 Biological Activity

Description (S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1[1].
Related Catalog
Target

VHL

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.

 Chemical & Physical Properties

Molecular Formula C31H47N5O4S
Molecular Weight 585.80

 Safety Information

Hazard Codes Xi
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