(Rac)-CP-601927 hydrochloride

Modify Date: 2024-01-03 11:31:17

(Rac)-CP-601927 hydrochloride Structure
(Rac)-CP-601927 hydrochloride structure
Common Name (Rac)-CP-601927 hydrochloride
CAS Number 230615-01-7 Molecular Weight 263.69
Density N/A Boiling Point N/A
Molecular Formula C12H13ClF3N Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (Rac)-CP-601927 hydrochloride


(Rac)-CP-601927 hydrochloride is the racemate of CP-601927. CP-601927 is a nAChR agonist with Ki values 1.2 nM and 102 nM for α4β2 and α3β4 nAChR, respectively[1].

 Names

Name (Rac)-CP-601927 hydrochloride

 (Rac)-CP-601927 hydrochloride Biological Activity

Description (Rac)-CP-601927 hydrochloride is the racemate of CP-601927. CP-601927 is a nAChR agonist with Ki values 1.2 nM and 102 nM for α4β2 and α3β4 nAChR, respectively[1].
Related Catalog
In Vitro CP-601927 induces significant antidepressant-like effects in mice. CP-601927 could decrease cholinergic signaling as a result of its reduced efficacy or via desensitization of α4β2* nAChRs[1].
References

[1]. Yann S Mineur, et al. α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties. Behav Pharmacol. 2011 Aug;22(4):291-9.

 Chemical & Physical Properties

Molecular Formula C12H13ClF3N
Molecular Weight 263.69
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