(Rac)-CP-601927 hydrochloride

Modify Date: 2025-08-28 12:12:21

(Rac)-CP-601927 hydrochloride structure	Common Name	(Rac)-CP-601927 hydrochloride
	CAS Number	230615-01-7	Molecular Weight	263.69
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₃ClF₃N	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (Rac)-CP-601927 hydrochloride

(Rac)-CP-601927 hydrochloride is the racemate of CP-601927. CP-601927 is a nAChR agonist with Ki values 1.2 nM and 102 nM for α4β2 and α3β4 nAChR, respectively[1].

Name	(Rac)-CP-601927 hydrochloride

Description	(Rac)-CP-601927 hydrochloride is the racemate of CP-601927. CP-601927 is a nAChR agonist with Ki values 1.2 nM and 102 nM for α4β2 and α3β4 nAChR, respectively[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
In Vitro	CP-601927 induces significant antidepressant-like effects in mice. CP-601927 could decrease cholinergic signaling as a result of its reduced efficacy or via desensitization of α4β2* nAChRs[1].
References	[1]. Yann S Mineur, et al. α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties. Behav Pharmacol. 2011 Aug;22(4):291-9.

Molecular Formula	C₁₂H₁₃ClF₃N
Molecular Weight	263.69

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