230615-01-7

230615-01-7 structure
230615-01-7 structure
  • Name: (Rac)-CP-601927 hydrochloride
  • Chemical Name: (Rac)-CP-601927 hydrochloride
  • CAS Number: 230615-01-7
  • Molecular Formula: C12H13ClF3N
  • Molecular Weight: 263.69
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
  • Create Date: 2021-10-30 17:48:05
  • Modify Date: 2024-01-03 11:31:17
  • (Rac)-CP-601927 hydrochloride is the racemate of CP-601927. CP-601927 is a nAChR agonist with Ki values 1.2 nM and 102 nM for α4β2 and α3β4 nAChR, respectively[1].

Name (Rac)-CP-601927 hydrochloride
Description (Rac)-CP-601927 hydrochloride is the racemate of CP-601927. CP-601927 is a nAChR agonist with Ki values 1.2 nM and 102 nM for α4β2 and α3β4 nAChR, respectively[1].
Related Catalog
In Vitro CP-601927 induces significant antidepressant-like effects in mice. CP-601927 could decrease cholinergic signaling as a result of its reduced efficacy or via desensitization of α4β2* nAChRs[1].
References

[1]. Yann S Mineur, et al. α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties. Behav Pharmacol. 2011 Aug;22(4):291-9.

Molecular Formula C12H13ClF3N
Molecular Weight 263.69