XL 188
Modify Date: 2025-09-25 10:11:23
XL 188 structure
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Common Name | XL 188 | ||
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| CAS Number | 2305045-76-3 | Molecular Weight | 574.71 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H42N6O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of XL 188XL 188 is a potent and selective USP7 inhibitor with IC50 values of 90 nM and 193 nM for USP7 full-length and catalytic domain enzyme, respectively. XL 188 can be used in research of cancer[1]. |
| Name | XL 188 |
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| Description | XL 188 is a potent and selective USP7 inhibitor with IC50 values of 90 nM and 193 nM for USP7 full-length and catalytic domain enzyme, respectively. XL 188 can be used in research of cancer[1]. |
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| Related Catalog | |
| In Vitro | Xl 188 (1-20 μm; 16 h; MCF7 细胞) 促进 USP7 依赖性 HDM2 的丢失和 p53 和 p21 的增加[1]。 Western Blot Analysis[1] Cell Line: MCF7 cells Concentration: 1, 5, 10, and 20μM Incubation Time: 16 hours Result: Had the loss of HDM2 accompanied by an increase in downstream tumor suppressors p21 and p53. |
| References |
| Molecular Formula | C32H42N6O4 |
|---|---|
| Molecular Weight | 574.71 |