1426153-46-9
1426153-46-9 structure
- Name: XL-001
- Chemical Name: XL-001
- CAS Number: 1426153-46-9
- Molecular Formula: C25H30N2O3S
- Molecular Weight: 438.586
- Create Date: 2020-01-11 20:02:49
- Modify Date: 2024-09-25 17:17:03
-
XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM; inhibits in a dose-dependent fashion the fibrogenic response induced by CB2 overexpression, CB2 agonist or transforming growth factor-β1, ameliorates kidney injury, fibrosis and inflammation in both the obstruction and ischemia/reperfusion models.
| Name | XL-001 |
|---|
| Description | XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM; inhibits in a dose-dependent fashion the fibrogenic response induced by CB2 overexpression, CB2 agonist or transforming growth factor-β1, ameliorates kidney injury, fibrosis and inflammation in both the obstruction and ischemia/reperfusion models. |
|---|---|
| References | References 1. Zhou L, et al. Kidney Int. 2018 Aug 6. pii: S0085-2538(18)30397-1. View Related Products by Target Cannabinoid Receptor |
| Molecular Formula | C25H30N2O3S |
|---|---|
| Molecular Weight | 438.586 |