RAS GTPase inhibitor 1
Modify Date: 2025-09-09 10:13:29
RAS GTPase inhibitor 1 structure
|
Common Name | RAS GTPase inhibitor 1 | ||
|---|---|---|---|---|
| CAS Number | 2252242-32-1 | Molecular Weight | 565.99 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H28ClF4N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RAS GTPase inhibitor 1RAS GTPase inhibitor 1 (example 51) is a RAS GTPase inhibitor with anti-tumor activity, extracted from patent WO2018212774A1. RAS GTPase inhibitor 1 (example 51) exhibits an EC50 less than 1 μM for at least one nucleotide exchange and an IC50 less than 1 μM in H727 cells[1]. |
| Name | RAS GTPase inhibitor 1 |
|---|
| Description | RAS GTPase inhibitor 1 (example 51) is a RAS GTPase inhibitor with anti-tumor activity, extracted from patent WO2018212774A1. RAS GTPase inhibitor 1 (example 51) exhibits an EC50 less than 1 μM for at least one nucleotide exchange and an IC50 less than 1 μM in H727 cells[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: < 1 μM (H727 cells)[1]. EC50: < 1 μM (nucleotide exchange)[1]. |
| References |
| Molecular Formula | C27H28ClF4N5O2 |
|---|---|
| Molecular Weight | 565.99 |
| InChIKey | LEDWHIWAVNXCBJ-VZYDHVRKSA-N |
| SMILES | CCC(Nc1nc(Nc2ccc(F)c(Cl)c2)nc2c(C3=CCNCC3)cccc12)C1CC1.O=C(O)C(F)(F)F |