2252242-32-1

2252242-32-1 structure

Name: RAS GTPase inhibitor 1
Chemical Name: RAS GTPase inhibitor 1
CAS Number: 2252242-32-1
Molecular Formula: C₂₇H₂₈ClF₄N₅O₂
Molecular Weight: 565.99
Catalog: Signaling Pathways GPCR/G Protein Ras
Create Date: 2020-04-10 15:44:03
Modify Date: 2025-09-09 10:13:29
RAS GTPase inhibitor 1 (example 51) is a RAS GTPase inhibitor with anti-tumor activity, extracted from patent WO2018212774A1. RAS GTPase inhibitor 1 (example 51) exhibits an EC50 less than 1 μM for at least one nucleotide exchange and an IC50 less than 1 μM in H727 cells[1].

Name	RAS GTPase inhibitor 1

Description	RAS GTPase inhibitor 1 (example 51) is a RAS GTPase inhibitor with anti-tumor activity, extracted from patent WO2018212774A1. RAS GTPase inhibitor 1 (example 51) exhibits an EC50 less than 1 μM for at least one nucleotide exchange and an IC50 less than 1 μM in H727 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
Target	IC50: < 1 μM (H727 cells)[1]. EC50: < 1 μM (nucleotide exchange)[1].
References	[1]. WATERSON, Alex G, et al. QUINAZOLINE COMPOUNDS AS MODULATORS OF RAS SIGNALING. Patent. WO2018212774A1.

Molecular Formula	C₂₇H₂₈ClF₄N₅O₂
Molecular Weight	565.99