Antitumor agent-104

Modify Date: 2024-04-06 12:06:22

Antitumor agent-104 structure	Common Name	Antitumor agent-104
	CAS Number	2245272-16-4	Molecular Weight	556.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₃₃FN₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Antitumor agent-104

Antitumor agent-104 (Compound 9) is an antitumor agent by inhibiting DNA damage repair in tumors. Antitumor agent-104 inhibits PARP1 enzymatic activity and the PAR protein level. Antitumor agent-104 also inhibits the expression of CDK12[1].

Name	Antitumor agent-104

Description	Antitumor agent-104 (Compound 9) is an antitumor agent by inhibiting DNA damage repair in tumors. Antitumor agent-104 inhibits PARP1 enzymatic activity and the PAR protein level. Antitumor agent-104 also inhibits the expression of CDK12[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> CDK Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
References	[1]. Lin S, et al. Synthesis of Novel Dual Target Inhibitors of CDK12 and PARP1 and Their Antitumor Activities in HER2-Positive Breast Cancers. ACS Omega. 2023 Jul 7;8(28):25574-25581.

Molecular Formula	C₃₁H₃₃FN₆O₃
Molecular Weight	556.63

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Antitumor agent-104

Use of Antitumor agent-104

Names

Antitumor agent-104 Biological Activity

Chemical & Physical Properties