Azido-PEG3-amide-C3-triethoxysilane

Modify Date: 2024-01-23 18:10:42

Azido-PEG3-amide-C3-triethoxysilane Structure
Azido-PEG3-amide-C3-triethoxysilane structure
Common Name Azido-PEG3-amide-C3-triethoxysilane
CAS Number 2243566-43-8 Molecular Weight 450.60
Density N/A Boiling Point N/A
Molecular Formula C18H38N4O7Si Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG3-amide-C3-triethoxysilane


Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG3-amide-C3-triethoxysilane

 Azido-PEG3-amide-C3-triethoxysilane Biological Activity

Description Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H38N4O7Si
Molecular Weight 450.60