TCO-PEG3-triethoxysilane

Modify Date: 2025-09-21 10:59:43

TCO-PEG3-triethoxysilane structure	Common Name	TCO-PEG3-triethoxysilane
	CAS Number	2250217-32-2	Molecular Weight	576.80
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₅₂N₂O₉Si	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TCO-PEG3-triethoxysilane

TCO-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	TCO-PEG3-amide-C3-triethoxysilane
Synonym	More Synonyms

Description	TCO-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₇H₅₂N₂O₉Si
Molecular Weight	576.80
InChIKey	ZXQAFZQBZKLJGI-FPLPWBNLSA-N
SMILES	CCO[Si](CCCNC(=O)CCOCCOCCOCCNC(=O)OC1CCC=CCCC1)(OCC)OCC

MFCD31811541

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Product Name: TCO-PEG3-triethoxysilane
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