1807512-36-2

1807512-36-2 structure

Name: Azido-PEG3-C3-OH
Chemical Name: Azido-PEG3-(CH2)3OH
CAS Number: 1807512-36-2
Molecular Formula: C₉H₁₉N₃O₄
Molecular Weight: 233.265
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-27 08:09:15
Modify Date: 2024-01-09 14:37:38
Azido-PEG3-C3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG3-(CH2)3OH
Synonyms	AZIDO-PEG3-(CH2)3OH

Description	Azido-PEG3-C3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562