Azido-C1-PEG3-C3-NH2

Modify Date: 2024-01-09 16:00:54

Azido-C1-PEG3-C3-NH2 Structure
Azido-C1-PEG3-C3-NH2 structure
Common Name Azido-C1-PEG3-C3-NH2
CAS Number 1162336-72-2 Molecular Weight 246.30700
Density N/A Boiling Point N/A
Molecular Formula C10H22N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-C1-PEG3-C3-NH2


Azido-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3-(2-(2-(3-azidopropoxy)ethoxy)ethoxy)propan-1-amine
Synonym More Synonyms

 Azido-C1-PEG3-C3-NH2 Biological Activity

Description Azido-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H22N4O3
Molecular Weight 246.30700
Exact Mass 246.16900
PSA 103.46000
LogP 1.23846

 Safety Information

Hazard Codes Xi

 Synonyms

n3-tota 1-azido-4,7,10-trioxa-13-tridecanamine