Biotin-C1-PEG3-C3-amine TFA

Modify Date: 2025-08-26 09:44:31

Biotin-C1-PEG3-C3-amine TFA Structure
Biotin-C1-PEG3-C3-amine TFA structure
Common Name Biotin-C1-PEG3-C3-amine TFA
CAS Number 1334172-59-6 Molecular Weight 560.63
Density N/A Boiling Point N/A
Molecular Formula C22H39F3N4O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-C1-PEG3-C3-amine TFA


Biotin-C1-PEG3-C3-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-C1-PEG3-C3-amine TFA
Synonym More Synonyms

 Biotin-C1-PEG3-C3-amine TFA Biological Activity

Description Biotin-C1-PEG3-C3-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C22H39F3N4O7S
Molecular Weight 560.63

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD13184983
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