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2028288-77-7

2028288-77-7 structure
2028288-77-7 structure
  • Name: TCO-C3-PEG3-C3-amine
  • Chemical Name: TCO-C3-PEG3-C3-amine
  • CAS Number: 2028288-77-7
  • Molecular Formula: C19H36N2O5
  • Molecular Weight: 372.50
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:07:44
  • Modify Date: 2024-01-02 14:35:20
  • TCO-C3-PEG3-C3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name TCO-C3-PEG3-C3-amine
Synonyms MFCD30458038
Description TCO-C3-PEG3-C3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C19H36N2O5
Molecular Weight 372.50
Hazard Codes Xi