Biotin-C1-PEG3-C3-amine TFA

Modify Date: 2024-01-12 18:06:29

Biotin-C1-PEG3-C3-amine TFA structure	Common Name	Biotin-C1-PEG3-C3-amine TFA
	CAS Number	1334172-59-6	Molecular Weight	560.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₃₉F₃N₄O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Biotin-C1-PEG3-C3-amine TFA

Biotin-C1-PEG3-C3-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotin-C1-PEG3-C3-amine TFA
Synonym	More Synonyms

Description	Biotin-C1-PEG3-C3-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₂₂H₃₉F₃N₄O₇S
Molecular Weight	560.63

Hazard Codes	Xi

MFCD13184983