BAY 2416964

Modify Date: 2025-08-25 19:39:37

BAY 2416964 Structure
BAY 2416964 structure
Common Name BAY 2416964
CAS Number 2242464-44-2 Molecular Weight 387.82
Density 1.42±0.1 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C18H18ClN5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BAY 2416964


AHR antagonist 3 is a 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamide compound and an aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. AHR antagonist 3 has anti-cancer effects[1].

 Names

Name AHR antagonist 3

 BAY 2416964 Biological Activity

Description AHR antagonist 3 is a 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamide compound and an aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. AHR antagonist 3 has anti-cancer effects[1].
Related Catalog
Target

IC50: 341 nM (Aryl hydrocarbon receptor (AHR))[1]

In Vitro AHR antagonist 3 (Example 192) induces AHR-regulated gene CYP1A1 expression in a human monocytic U937 cells with an IC50 of 4.3 nM[1].
References

[1]. Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1

 Chemical & Physical Properties

Density 1.42±0.1 g/cm3(Predicted)
Molecular Formula C18H18ClN5O3
Molecular Weight 387.82

 Safety Information

Hazard Codes Xn
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