LOXO-292
Modify Date: 2025-08-25 11:20:03
LOXO-292 structure
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Common Name | LOXO-292 | ||
|---|---|---|---|---|
| CAS Number | 2222755-14-6 | Molecular Weight | 553.61 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H31N9O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LOXO-292RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively [1]. |
| Name | RET-IN-1 |
|---|---|
| Synonym | More Synonyms |
| Description | RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively [1]. |
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| Related Catalog | |
| Target |
IC50: 1 nM (RETWT), 7 nM (RETV804M), 101 nM (RETG810R) |
| References |
| Molecular Formula | C29H31N9O3 |
|---|---|
| Molecular Weight | 553.61 |
| Storage condition | 2-8℃ |
| LOXO-292 |