1-Methylguanidine hydrochloride

Modify Date: 2025-08-19 20:55:58

1-Methylguanidine hydrochloride structure	Common Name	1-Methylguanidine hydrochloride
	CAS Number	21770-81-0	Molecular Weight	109.55800
	Density	1.22 g/mL at 20 °C(lit.)	Boiling Point	72 °C
	Molecular Formula	C₂H₈ClN₃	Melting Point	-20 °C
	MSDS	Chinese USA	Flash Point	65 °F
	Symbol	GHS07	Signal Word	Warning

Use of 1-Methylguanidine hydrochloride

Name	2-methylguanidine,hydrochloride
Synonym	More Synonyms

Density	1.22 g/mL at 20 °C(lit.)
Boiling Point	72 °C
Melting Point	-20 °C
Molecular Formula	C₂H₈ClN₃
Molecular Weight	109.55800
Flash Point	65 °F
Exact Mass	109.04100
PSA	61.90000
LogP	1.09220
Index of Refraction	n20/D 1.4279(lit.)
Water Solubility	insoluble

1-Methylguanidine hydrochloride MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MF3990000

CHEMICAL NAME :: Guanidine, 1-methyl-, hydrochloride

CAS REGISTRY NUMBER :: 21770-81-0

LAST UPDATED :: 199009

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C2-H7-N3.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 375 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 28,251,1926

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 680 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 1,434,1952

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04013

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319
Precautionary Statements	P280-P301 + P312 + P330-P305 + P351 + P338-P337 + P313
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S26-S36/37
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	MF3990000

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1-Methylguanidine hydrochloride

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MFCD00012576