Ac-Ile-Glu-Pro-Asp-pNA

Modify Date: 2024-01-07 14:27:34

Ac-Ile-Glu-Pro-Asp-pNA Structure
Ac-Ile-Glu-Pro-Asp-pNA structure
Common Name Ac-Ile-Glu-Pro-Asp-pNA
CAS Number 216757-29-8 Molecular Weight 634.635
Density 1.4±0.1 g/cm3 Boiling Point 1096.9±65.0 °C at 760 mmHg
Molecular Formula C28H38N6O11 Melting Point N/A
MSDS N/A Flash Point 617.2±34.3 °C

 Use of Ac-Ile-Glu-Pro-Asp-pNA


N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a granzyme B substrate that allows accurate measurement of granzyme B activity[1].

 Names

Name (4S)-4-[[(2S,3S)-2-acetamido-3-methylpentanoyl]amino]-5-[(2S)-2-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-oxopentanoic acid
Synonym More Synonyms

 Ac-Ile-Glu-Pro-Asp-pNA Biological Activity

Description N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a granzyme B substrate that allows accurate measurement of granzyme B activity[1].
Related Catalog
References

[1]. Kristina Fritsch, et al. Suppression of granzyme B activity and caspase-3 activation in leukaemia cells constitutively expressing the protease inhibitor 9. Ann Hematol. 2013 Dec;92(12):1603-9.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1096.9±65.0 °C at 760 mmHg
Molecular Formula C28H38N6O11
Molecular Weight 634.635
Flash Point 617.2±34.3 °C
Exact Mass 634.259827
PSA 257.13000
LogP 2.01
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.592
Storage condition -20°C

 Safety Information

Hazard Codes Xi

 Synonyms

L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-nitrophenyl)-
N-Acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-nitrophenyl)-L-α-asparagine
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