USP25 and 28 inhibitor AZ-1

Modify Date: 2024-01-03 10:31:49

USP25 and 28 inhibitor AZ-1 structure	Common Name	USP25 and 28 inhibitor AZ-1
	CAS Number	2165322-94-9	Molecular Weight	422.21
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₆BrF₄NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of USP25 and 28 inhibitor AZ-1

USP25/28 inhibitor AZ1 (AZ1) is a potent, selective, noncompetitive, dual ubiquitin specific protease (USP) 25/28 inhibitor with IC50s of 0.7 μM and 0.6 μM, respectively. USP25/28 inhibitor AZ1 reduces cell viability across a range of cancer cell lines[1].

Name	USP25/28 inhibitor AZ1

Description	USP25/28 inhibitor AZ1 (AZ1) is a potent, selective, noncompetitive, dual ubiquitin specific protease (USP) 25/28 inhibitor with IC50s of 0.7 μM and 0.6 μM, respectively. USP25/28 inhibitor AZ1 reduces cell viability across a range of cancer cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase
Target	IC50: 0.7 nM (USP25) and 0.6 nM (USP28)[1]
References	[1]. Wrigley JD, et al. Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating EnzymeSubfamily. ACS Chem Biol. 2017 Dec 15;12(12):3113-3125.

Molecular Formula	C₁₇H₁₆BrF₄NO₂
Molecular Weight	422.21

DC Chemicals Limited
China
Product Name: USP25 and 28 inhibitor AZ-1
Price: $550.0/100mg $950.0/250mg $1900.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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