KH 176
Modify Date: 2025-08-25 09:15:09
KH 176 structure
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Common Name | KH 176 | ||
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| CAS Number | 2162149-24-6 | Molecular Weight | 368.902 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H29ClN2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of KH 176KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders; retains brain microstructural coherence in the external capsule in Ndufs4 -/- mice and normalizes the increased lipid peroxidation in this area and the cerebral cortex, significantly improves rotarod and gait performance and reduces the degeneration of retinal ganglion cells in Ndufs4 -/- mice. Other Indication Phase 2 Clinical |
| Name | KH 176 |
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| Description | KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders; retains brain microstructural coherence in the external capsule in Ndufs4 -/- mice and normalizes the increased lipid peroxidation in this area and the cerebral cortex, significantly improves rotarod and gait performance and reduces the degeneration of retinal ganglion cells in Ndufs4 -/- mice. Other Indication Phase 2 Clinical |
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| References | References 1. de Haas R, et al. Sci Rep. 2017 Sep 15;7(1):11733. 2. Koene S, et al. Orphanet J Rare Dis. 2017 Oct 16;12(1):163. View Related Products by Target Other Targets Other Indication |
| Molecular Formula | C19H29ClN2O3 |
|---|---|
| Molecular Weight | 368.902 |
| InChIKey | HVFWCHDZDIRYBZ-MQZJHDQISA-N |
| SMILES | Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NC1CCCNC1)O2.Cl |