Virginiamycin M1

Modify Date: 2024-01-02 13:03:26

Virginiamycin M1 structure	Common Name	Virginiamycin M1
	CAS Number	21411-53-0	Molecular Weight	525.59300
	Density	1.26 g/cm3	Boiling Point	825.2ºC at 760 mmHg
	Molecular Formula	C₂₈H₃₅N₃O₇	Melting Point	165-170 °C
	MSDS	Chinese USA	Flash Point	452.9ºC

Use of Virginiamycin M1

Pristinamycin IIA (RP 12536) is a macrocyclic lactone peptolide antibiotic, derived from Streptomyces pristinaespiralis, which is a member of the streptogramin A group of antibiotics[1].

Name	pristinamycin IIA
Synonym	More Synonyms

Description	Pristinamycin IIA (RP 12536) is a macrocyclic lactone peptolide antibiotic, derived from Streptomyces pristinaespiralis, which is a member of the streptogramin A group of antibiotics[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	Bacterial[1]
References	[1]. Sezonov G, et al. Complete conversion of antibiotic precursor to pristinamycin IIA by overexpression of Streptomyces pristinaespiralis biosynthetic genes. Nat Biotechnol. 1997 Apr;15(4):349-53.

Density	1.26 g/cm3
Boiling Point	825.2ºC at 760 mmHg
Melting Point	165-170 °C
Molecular Formula	C₂₈H₃₅N₃O₇
Molecular Weight	525.59300
Flash Point	452.9ºC
Exact Mass	525.24800
PSA	139.04000
LogP	2.92610
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.586
Storage condition	-20°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3.0

Purification and characterization of virginiamycin M1 reductase from Streptomyces virginiae.

Antimicrob. Agents Chemother. 42 , 2985-2988, (1998)

Virginiamycin M1 (VM1), produced by Streptomyces virginiae, is a polyunsaturated macrocyclic lactone antibiotic belonging to the virginiamycin A group. S. virginiae possesses an activity which stereos...

PapR6, a putative atypical response regulator, functions as a pathway-specific activator of pristinamycin II biosynthesis in Streptomyces pristinaespiralis.

J. Bacteriol. 197(3) , 441-50, (2015)

There are up to seven regulatory genes in the pristinamycin biosynthetic gene cluster of Streptomyces pristinaespiralis, which infers a complicated regulation mechanism for pristinamycin production. I...

VisG is eβential for biosynthesis of virginiamycin S, a streptogramin type B antibiotic, as a provider of the nonproteinogenic amino acid phenylglycine Fitria Ningsih, Shigeru Kitani, et al.

Microbiology 167 , 3213 - 3220, (2011)

Vernamycin A

Staphylomycin M1

STAPHYLOMYCIN

Antibiotic PA-114A1

pristinamycin component IIA

VIRGINIAMYCINE

MIKAMYCIN A

Pristinamycin IIA

VIRGINIAMYCIN M1

Streptogramin A