蛎灰菌素A

更新时间:2024-01-02 13:03:26

蛎灰菌素A结构式
蛎灰菌素A结构式
品牌特惠专场
常用名 蛎灰菌素A 英文名 Virginiamycin M1
CAS号 21411-53-0 分子量 525.59300
密度 1.26 g/cm3 沸点 825.2ºC at 760 mmHg
分子式 C28H35N3O7 熔点 165-170 °C
MSDS 中文版 美版 闪点 452.9ºC

 蛎灰菌素A用途


Pristinamycin IIA (RP 12536) 是一种大环内酯类抗生素, 来源于 Streptomyces pristinaespiralis,是 streptogramin A 组抗生素。

 蛎灰菌素A名称

中文名 蛎灰菌素A
英文名 pristinamycin IIA
中文别名 维吉尼霉素M1
英文别名 更多

 蛎灰菌素A生物活性

描述 Pristinamycin IIA (RP 12536) 是一种大环内酯类抗生素, 来源于 Streptomyces pristinaespiralis,是 streptogramin A 组抗生素。
相关类别
靶点

Bacterial[1]

参考文献

[1]. Sezonov G, et al. Complete conversion of antibiotic precursor to pristinamycin IIA by overexpression of Streptomyces pristinaespiralis biosynthetic genes. Nat Biotechnol. 1997 Apr;15(4):349-53.

 蛎灰菌素A物理化学性质

密度 1.26 g/cm3
沸点 825.2ºC at 760 mmHg
熔点 165-170 °C
分子式 C28H35N3O7
分子量 525.59300
闪点 452.9ºC
精确质量 525.24800
PSA 139.04000
LogP 2.92610
外观性状 淡黄色至棕褐色晶体、粉末或块状
蒸汽压 0mmHg at 25°C
折射率 1.586
储存条件 -20°C

 蛎灰菌素A安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport
WGK德国 3.0

 蛎灰菌素A文献3

更多文献
Purification and characterization of virginiamycin M1 reductase from Streptomyces virginiae.

Antimicrob. Agents Chemother. 42 , 2985-2988, (1998)

Virginiamycin M1 (VM1), produced by Streptomyces virginiae, is a polyunsaturated macrocyclic lactone antibiotic belonging to the virginiamycin A group. S. virginiae possesses an activity which stereos...

PapR6, a putative atypical response regulator, functions as a pathway-specific activator of pristinamycin II biosynthesis in Streptomyces pristinaespiralis.

J. Bacteriol. 197(3) , 441-50, (2015)

There are up to seven regulatory genes in the pristinamycin biosynthetic gene cluster of Streptomyces pristinaespiralis, which infers a complicated regulation mechanism for pristinamycin production. I...

VisG is eβential for biosynthesis of virginiamycin S, a streptogramin type B antibiotic, as a provider of the nonproteinogenic amino acid phenylglycine Fitria Ningsih, Shigeru Kitani, et al.

Microbiology 167 , 3213 - 3220, (2011)

 蛎灰菌素A英文别名

Vernamycin A
Staphylomycin M1
STAPHYLOMYCIN
Antibiotic PA-114A1
pristinamycin component IIA
VIRGINIAMYCINE
MIKAMYCIN A
Pristinamycin IIA
VIRGINIAMYCIN M1
Streptogramin A
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