23152-29-6

23152-29-6 structure

Name: Virginiamycin S1
Chemical Name: virginiamycin S1
CAS Number: 23152-29-6
Molecular Formula: C₄₃H₄₉N₇O₁₀
Molecular Weight: 823.89000
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2017-12-10 15:54:36
Modify Date: 2024-01-08 13:51:14
Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections[1][2].

Name	virginiamycin S1
Synonyms	virginiamycin s1 (staphylomycin s, pa 114b2, antibiotic 899, antibiotic pa 114b2, antibiotic 1745z3b, factor s ) avilamycin

Description	Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Ningsih F, et al. VisG is essential for biosynthesis of virginiamycin S, a streptogramin type B antibiotic, as a provider of the nonproteinogenic amino acid phenylglycine. Microbiology. 2011 Nov;157(Pt 11):3213-20. [2]. Ge B, et al. Purification and characterization of virginiamycin M1 reductase from Streptomyces virginiae. Sci Rep. 2017 Sep 8;7(1):11017.

RIDADR	NONH for all modes of transport