Lycoramine free base

Modify Date: 2024-01-06 14:45:45

Lycoramine free base Structure
Lycoramine free base structure
Common Name Lycoramine free base
CAS Number 21133-52-8 Molecular Weight 289.36900
Density 1.25 Boiling Point 436.4ºC at 760mmHg
Molecular Formula C17H23NO3 Melting Point 122-124ºC
MSDS N/A Flash Point 217.7ºC

 Use of Lycoramine free base


Lycoramine, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor[1][2].

 Names

Name Lycoramine
Synonym More Synonyms

 Lycoramine free base Biological Activity

Description Lycoramine, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor[1][2].
Related Catalog
Target

AChE[1]

References

[1]. Yuan Y, et, al. Online acetylcholinesterase inhibition evaluation by high-performance liquid chromatography-mass spectrometry hyphenated with an immobilized enzyme reactor. J Chromatogr A. 2020 Jan 4; 1609:460506.

[2]. IRWIN RL, et, al. Cholinesterase inhibition by galanthamine and lycoramine. Biochem Pharmacol. 1960 May; 3:147-8.

 Chemical & Physical Properties

Density 1.25
Boiling Point 436.4ºC at 760mmHg
Melting Point 122-124ºC
Molecular Formula C17H23NO3
Molecular Weight 289.36900
Flash Point 217.7ºC
Exact Mass 289.16800
PSA 41.93000
LogP 2.01220
Vapour Pressure 2.17E-08mmHg at 25°C
Index of Refraction 1.614
Storage condition 2-8°C

 Synonyms

(+-)-Lycoramin
Dihydrogalanthamine
(4aS,6S,8aR)-4a,5,7,8,9,10,11,12-Octahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol
1,2-Dihydrogalanthamine
UNII-TAG8LU84K2
(-)-lycoramine
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