21133-52-8

21133-52-8 structure

Name: Lycoramine free base
Chemical Name: Lycoramine
CAS Number: 21133-52-8
Molecular Formula: C₁₇H₂₃NO₃
Molecular Weight: 289.36900
Catalog: API Nervous system medication Cholinergic
Create Date: 2018-07-30 16:34:16
Modify Date: 2024-01-06 14:45:45
Lycoramine, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor[1][2].

Name	Lycoramine
Synonyms	(+-)-Lycoramin Dihydrogalanthamine (4aS,6S,8aR)-4a,5,7,8,9,10,11,12-Octahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 1,2-Dihydrogalanthamine UNII-TAG8LU84K2 (-)-lycoramine

Description	Lycoramine, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	AChE[1]
References	[1]. Yuan Y, et, al. Online acetylcholinesterase inhibition evaluation by high-performance liquid chromatography-mass spectrometry hyphenated with an immobilized enzyme reactor. J Chromatogr A. 2020 Jan 4; 1609:460506. [2]. IRWIN RL, et, al. Cholinesterase inhibition by galanthamine and lycoramine. Biochem Pharmacol. 1960 May; 3:147-8.