Cbz-PEG2-bromide

Modify Date: 2025-08-27 13:34:33

Cbz-PEG2-bromide Structure
Cbz-PEG2-bromide structure
Common Name Cbz-PEG2-bromide
CAS Number 2100283-00-7 Molecular Weight 346.22
Density N/A Boiling Point N/A
Molecular Formula C14H20BrNO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cbz-PEG2-bromide


Cbz-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Cbz-PEG2-bromide

 Cbz-PEG2-bromide Biological Activity

Description Cbz-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Molecular Formula C14H20BrNO4
Molecular Weight 346.22
InChIKey GRGPUJRSMCXZNT-UHFFFAOYSA-N
SMILES O=C(NCCOCCOCCBr)OCc1ccccc1
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